Emily Dickinson Lexicon

DIS-AF-FEC'TION, n.

1. Alienation of affection, attachment, or good will; want of affection; or more generally, positive enmity, dislike, or unfriendliness; disloyalty. It generally signifies more than indifference; as, the disaffection of people to their prince or government; the disaffection of allies; disaffection to religion.
2. Disorder; bad constitution; in a physical sense. [Little used.] – Wiseman.